The Science

The Science: The Endocannabinoid System

Recent research into the human endocannabinoid system revealed the system itself, how it works and the consequences of an insufficiency upon the human body.

“More importantly, modulating the activity of the endocannabinoid system turned out to hold therapeutic promise in a wide range of diseases and pathological conditions, ranging from mood and anxiety disorders, movement disorders such as Parkinson’s and Huntington’s disease, neuropathic pain, multiple sclerosis and spinal cord injury, to cancer, atherosclerosis, myocardial infarction, stroke, hypertension, glaucoma, obesity/metabolic syndrome, and osteoporosis, to name just a few.” (Pharmacological Review, September 2006, 58(3):389-462) In other words – the human body possesses a system designed to use cannabinoids. The use of cannabis to treat pain traces its roots back 3000 years BC where in ancient Chinese and Indian texts; the plant was used to treat pain.”

Additionally, in a study published in the Alcohol and Alcoholism, Volume 40, No. 1, pp 2-14 2005, researchers from .Madrid Spain concluded

“Since the discovery of anandamide, the increasing information on the physiological roles played by the endogenous cannabinoid system and its contribution to pathology has led to this signaling system becoming more important in neurobiology. The intense pharmacological research based on this information has yielded, in a very short time, potent, selective drugs targeting the endogenous cannabinoid system that have opened up new avenues for the understanding and treatment of major diseases including cancer, pain, neurodegeneration, anxiety and addiction. This is a very promising starting point for a new age that takes over from the ancient use of Cannabis as a medicine. Now is the time for clinical trials aimed at evaluating the efficacy of cannabinoid drugs in disorders lacking effective therapeutic approaches, such as alcoholism?”

The relatively recent discovery of the endogenous cannabinoid system as well as its effects on the human body, demand that we expand both our knowledge of the system itself but also the dynamics of exactly how cannabis reacts in the body. Furthermore, we need to learn exactly what a lack of cannabis means to the receptor sights.

“Our bodies already produce cannabinoids which are also present in marijuana. Cannabinoids influence various body processes such as pain and inflammation. Therefore, if someone consumes marijuana, it can assist those natural chemicals to function more efficiently. (The Hemp Connoisseur, May 2015, Parkinson’s disease: The Potential of Cannabis therapy, page 49. Dr. Nicola Davies)

It seems some individuals had at least an elementary understanding of the effects of cannabis on the human body even as America was criminalizing the use of cannabis.